Since the 1970s, studies and research have been carried out by scientists in Peru, Germany, Austria, England and other countries, to find out more about the powerful healing properties of Cat's Claw. Today, mainly by word of mouth, it has become one of the best selling herbs in the USA. Not since quinine was discovered in the bark of a Peruvian tree during the seventeenth century had any other rainforest plant ever prompted worldwide attention.
The most attention was given to the oxindole alkaloids found in the bark and roots of Cats Claw, which have been documented to stimulate the immune system. It is these seven different alkaloids that are credited with having a variety of different medicinal and healing properties. The most immunologically active alkaloid is believed to be Isopteropodin (Isomer A), which increases the immune response in the body and act as antioxidants to rid the body of free radicals. Compounds found in Cat's Claw may also work to kill viruses, bacteria, and other microorganisms that cause disease, and they work to inhibit healthy cells from becoming cancerous.
It has been suggested that Cat's claw extracts exert a direct anti-proliferative activity on MCF7 (a breast cancer cell line). This has led to its use as a adjunctive treatment for cancer and AIDS as well as other diseases that negatively impact the immunological system. In addition, the presence of glycosides, proanthocyanidins and beta sitosterol help provide anti-viral and anti-inflammatory support for the body. These alkaloids also exert a beneficial effect on memory. Cat's claw is considered a remarkably potent inhibitor of TNF-alpha production.
This herb's anti-inflammatory properties may help to relieve arthritis, gout, and other inflammatory problems. The primary mechanism for Cat's claw anti-inflammatory actions appears to be immunomodulation via suppression of TNF-alpha synthesis.
Cat's Claw may help create support for the intestinal and immune systems of the body, and may also creates intestinal support with its ability to cleanse the entire intestinal tract. This cleansing helps create support for people experiencing different stomach and bowel disorders, including: colitis, Crohn's disease, irritable bowel syndrome, and leaky bowel syndrome.
In addition, in one study, human volunteers who took Cat's claw for 8 weeks showed improved DNA repair.
Cat's Claw can often be found combined with other 'immune' herbs with similar healing properties such as Echinacea and may:
- reduce pain and inflammation of rheumatism, arthritis and other types of inflammatory problems.
- have anti-tumor and anti-cancer properties that inhibits cancerous cell formation.
- promote the healing of wounds.
- be useful for treatment of gastric ulcers and intestinal complaints
- help to relieve chronic pain.
- enhance immunity by stimulating the immune system.
- help people experiencing stomach and bowel disorders, including colitis, Crohn's disease, irritable bowel syndrome, leaky bowel syndrome, gastritis and duodenal ulcers, intestinal inflammation.
- help fight both viral and fungal infections such as Herpes and Candida