herb search

5-HTP

Used This Herb? How Would You Rate It?
12345678910


5-HTP Benefits

Contents

Most 5-HTP is extracted from the seeds of a woody climbing shrub native to West Africa, called the Griffonia simplicifolia plant.

What is 5-HTP?

5-HTP or "hydroxy L-tryptophane" (5-Hydroxytryphophan)  is a naturally-occurring amino acid and  is the precursor and metabolic intermediate in the biosynthesis of the neurotransmitters serotonin and melatonin from tryptophan. 5-HTP is converted to the neurotransmitter serotonin (5-HT), with the help of vitamin B6. This occurs both in nervous tissue and in the liver. 5-HTP crosses the blood-brain barrier  (while 5-HT does not). Supplementation with 5-HTP therefore increases production of Serotonin.

5-HTP health benefits

Widely used to help with obesity (dieting), PMS, migraines, depression, anxiety, insomnia and addictive behaviour. 5 HTP increases production of serotonin. Serotonin levels in the nervous system are essential for so many aspects of our daily lives. Serotonin is responsible for feelings of well being, satisfaction and for normal sleep patterns. Obesity, PMS, migraines, depression, anxiety, insomnia and addictive behavior have all been associated with low levels of serotonin. Serotonin plays an important role in controlling anger, aggression, body temperature, mood, sleep, human sexuality, appetite, and metabolism, as well as stimulating vomiting.

It is thought the hectic modern lifestyle of stress and bad eating habits lowers serotonin levels in the body. It is known that irritability, aggression, impatience, anxiety and worrying cause the body to release serotonin. This Serotonin then needs to be replenished by the body from the food you eat. But Serotonin is not found in large quantities in most diets so the body has to makes it itself from foods which contain L-tryptophan, such as chocolate, oats, bananas, dried dates, milk, yogurt, cottage cheese, meat, fish, turkey, chicken, sesame, chickpeas, and peanuts. Many people therefore crave the foods listed (fats and carbohydrates), especially when stressed, causing weight gain, depression, headaches, and muscle aches.

Atkins Diet - reduce cravings

Clinical studies have shown that supplementing with 5-HTP produces positive results in weight loss, anxiety and depression. It improves sleep patterns and reduces carbohydrate cravings in those on low carbohydrate diets (such as The Atkins Diet). Anyone using a weight loss program similar to the Atkins Diet could experience a reduction in serotonin levels due to the fact that carbohydrates stimulate serotonin production in the body. Serotonin release is triggered by a carbohydrate load (sugar etc.) and it is thought that's why we often crave Carbohydrates under stress as we want to stimulate this serotonin release. When the brain produces serotonin, tension is eased.  Conversely when the brain produces dopamine or norepinephrine (noradrenaline), we tend to think and act more quickly and are generally more alert. Therefore eating carbohydrates seems to have a calming effect, while proteins increase alertness.

Taking 5-HTP supplements can stop this craving for fats and carbohydrates, as well as providing the body with the means to control all those other functions listed above, such as anger, appetite and sleep.

Help with Depression and Anxiety

Some research has been done into 5-HTP and shows it has potential to help with depression and possibly anxiety, panic disorder, sleep disorders and obesity. 5-HTP seems to have the same effects as SSRI (Selective Serotonin Re-uptake Inhibitors) antidepressants.

Prescription drugs that raise serotonin levels are prescribed for all of these problems, but many people believe 5-HTP is a natural way to accomplish the same thing.

Dosage

Most research seems to suggest that 5-HTP is safe in the right dose. This seems to be no more than 100mg per day. 5-HTP is usually tolerated much better than traditional antidepressants. HOWEVER, it is important not to take more than 100mg per day, or other antidepressants at the same time.

Excess 5-HTP is thought to be metabolized and excreted, especially when taken with Vitamin B6.

It is widely recommended to take 5-HTP 30 mins before going to bed, as apart from producing Serotonin, 5-HTP also produces Melatonin, which is a sleep-inducing hormone. The usual dosage is either a 50mg or 100mg tablet. The effects of taking 5HTP can be felt within 10 to 30 mins.

Why not try some today and see if you too can reduce your cravings, stress and anger levels, as well as getting a good night's sleep!



5-HTP Herb Notes / Side Effects

If you are taking MAO inhibitors, anti-depressants or being treated for Parkinson's Disease, consult your Doctor first.

Tablets usually contain 50mg, or 100mg, of 5-HTP. Also look out for vitamin B6 in there as well (as Vit B6 is needed for 5-HTP conversion into serotonin).

It is important NOT to take more than 100mg 5-HTP per day. Also DON'T or other antidepressants at the same time. This is because a 5HTP overdose can lead to Serotonin Syndrome, which includes headaches, confusion, sweating and shivering, nausea and increased heart rate.

5-HTP is usually taken 30 mins before going to bed, as it produces Melatonin as well as Serotonin, and Melatonin is a sleep-inducing hormone. The effects of taking 5HTP can be felt within 10 to 30 mins.

Important: Click here to read our disclaimer

Where to buy 5-HTP

Olympian Labs 5 HTP Plus 100mg 30Caps
$15.49 from House of Nutrition
Jarrow 5 HTP 100mg 60Caps
$27.95 from House of Nutrition
Designs For Health 5 HTP Supreme 60 Caps
$38.00 from House of Nutrition
Jarrow 5 HTP 50mg 90Caps
$20.95 from House of Nutrition

Has 5-HTP worked for you?

This page is not a wiki so it is not editable like Wikipedia, however we would like to hear your information and comments and sometimes incorporate these into the articles.

Showing 1 post of 26 posts

Maya's avatarMaya

I started taking 5HTP after suffering from anxiety and mild depression. I had difficulties concentrating and I was just miserable. Ever since I started taking 5HTP I feel much better, I feel more accepting of things and I am able to concentrate for longer periods of time. I don't have this rage within me anymore, I don't have obsessive thoughts and I don't wonder around in my mind anymore. It also helps with apatite regulation (not that I need it) but I don't crave sweets, fatty and salty food as often.

I take 5HTP with L-tyrosine , L-Dopa (one of each in the morning) without food. After breakfast I take a vitamin supplement.

I only take 100 mg of 5HTP, 150mg of L-Dopa and 450 mg of L-tyrosine, it might be different for everybody but so far this works for me. I suggest that you do not take L-Dopa before going to bed because it will keep you awake, 5HTP itself before bed is fine.

Also, do not take 5HTP if you are on any medication (SSRIs, MAOs - Prozac, Zoloft etc). Do not take L-Dopa if you have Parkinson without talking to your doctor and do not take L-tyrosine if you have or have had a thyroid problem and have been taking medication for it, please consult your doctor.

View more »